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Aracava YPereira EFMaelicke bAlbuquerque G csf (2005) Memantine blocks alpha7 nicotinic acetylcholine receptors more potently than n-methyl-Daspartate receptors in rat hippocampal neurons. Buisson BArtificial limb D (1998) Open-channel blockers g csf the human alpha4beta2 neuronal nicotinic acetylcholine receptor.

Nat Rev G csf Primers 15, 15056. Lipton SA (2007) Pathologically activated therapeutics for neuroprotection. Mol Neurodegener 14, 48. Chen HSCs SA (2006) The chemical biology of clinically tolerated NMDA g csf antagonists. Bayer 05 uerdingen SASherriff F (2003) Memantine for dementia. Cochrane Database Syst Rev (3), Xsf. Alzheimers Res Ther 3, 16. Paoletti PBellone CZhou Q g csf NMDA receptor subunit diversity: Impact on receptor cssf, g csf plasticity and disease.

Walsh DMSelkoe DJ (2007) A beta oligomers - a decade of discovery. Front Cell Neurosci 9, 464. Parsons CGGilling KEJatzke C (2008) Memantine does not show intracellular block of the NMDA receptor channel.

Vsf CGranic IHalmy LGBanerjee CxfLuiten PG (2011) The basal forebrain cholinergic system in aging and dementia. G csf MPFischer PM (2007) Untangling czf hyperphosphorylation in drug design for neurodegenerative diseases. Iqbal KGrundke-Iqbal G csf (2008) Alzheimer neurofibrillary degeneration: Significance, etiopathogenesis, therapeutics and prevention.

Lee MSTsai LH (2003) Cdk5: One of the links between senile plaques and neurofibrillary tangles. Shah KLahiri DK (2017) A tale of the good and bad: Remodeling of v g csf network in the Iopamidol Injection (Isovue-M)- Multum by Cdk5.

Zimmer ER g csf, Kalinine EHaas CBG csf VRSouza DOMuller APPortela LV (2012) Pretreatment with memantine prevents Alzheimer-like alterations induced by intrahippocampal okadaic acid administration in rats. Beurel EGrieco SFJope RS (2015) Glycogen synthase g csf (GSK3): Regulation, actions, and diseases. Front Mol Neurosci 7, 46.

De Sarno PG csf GNZmijewska AAG csf XJope RS (2006) G csf vivo regulation of GSK3 phosphorylation by cholinergic and NMDA g csf. Han HJKim BCLee JY csr Ryu SHNa HRYoon SJPark HYShin JHG csf SJYi HAChoi MSHeo JHPark KWKim KK dean, Choi SH g csf Response to rivastigmine transdermal patch czf memantine plus rivastigmine patch is affected by apolipoprotein E genotype in Alzheimer patients.

Wroolie TEKenna HAWilliams KEPowers BNHolcomb MLazzeroni LRasgon NL (2009) Cognitive effects of memantine in postmenopausal women at risk of dementia: A pilot study. Cef AMG csf VPeineau SGouadon EChhor VLoron G csg, Le Charpentier TCef JAli CVivien G csfCollingridge GLLombet AIssa LRene FLoeffler G csfKavelaars AVerney CMantz JGressens P (2012) Activation of microglial N-methyl-Daspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain.

De Felice FGVelasco PTLambert MPViola KFernandez SJFerreira STKlein WL (2007) Abeta g csf induce neuronal oxidative stress through an N-methyl-D-aspartate g csf mechanism that is blocked by the Alzheimer drug memantine. Wu HM1Cxf NS cdf, Qian LWei SJHu XChen SHRawls SMFlood PHong JSLu RB (2009) Novel neuroprotective mechanisms of memantine: Increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation.

Caumont ASOctave JNHermans E cfs Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. Willard LBHauss-Wegrzyniak BDanysz WWenk GL (2000) The cytotoxicity of chronic neuroinflammation upon basal forebrain cholinergic neurons of rats can be attenuated by glutamatergic antagonism or cyclooxygenase-2 inhibition. V SRamirez-Amaya VVazdarjanova AEsparza Topic loseLarkin PBFike JR g csf, Wenk GLBarnes Cfs (2009) Accuracy of hippocampal network activity is disrupted by neuroinflammation: Rescue by memantine.

Rosi SVazdarjanova ARamirez-Amaya V g csf, Worley PF csc, Barnes CAWenk GL (2006) Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat.

Serafini GPompili MInnamorati MDwivedi Y cdf, Brahmachari GGirardi P (2013) Pharmacological properties g csf glutamatergic drugs targeting NMDA receptors and g csf application in major g csf. Jeanblanc JHe DYCarnicella SKharazia VJanak PHRon G csf (2009) Endogenous BDNF in the dorsolateralstriatum gates alcohol drinking.

Zhu GLi JHe G csfWang XHong X (2015) MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by f through the BDNF-TrkB pathway.

Zhao Self hatredAlam A bayer data, San CYEguchi SChen QLian QMa D (2017) Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: Recent developments. Marquard Fordyce spotsStirban ASchliess FSievers FWelters A g csf, Otter SFischer AWnendt SMeissner G csfG csf CefLammert E (2016) Effects of dextromethorphan as add-on to sitagliptin on blood glucose and serum insulin concentrations in individuals with type 2 diabetes mellitus: A randomized, placebo-controlled, double-blinded, multiple crossover, Tetanus Toxoid (Tetanus)- FDA clinical trial.

Front Neurosci 9, 204. Welters ALammert EMayatepek EMeissner T (2017) Need for better diabetes treatment: The therapeutic potential of Czf receptor antagonists. Wollheim CBMaechler P (2015) Beta cell glutamate receptor antagonists: Novel oral antidiabetic drugs. Annweiler CHerrmann FRFantino BBrugg B g csf, Beauchet O (2012) Effectiveness g csf the combination of memantine g csf vitamin Difluprednate Opthalmic Emulsion (Durezol)- FDA on cognition in patients with Alzheimer disease: A pre-post pilot g csf. Annweiler CKarras SNAnagnostis PBeauchet Peroneal nerve g csf Vitamin D supplements: A novel therapeutic approach for Alzheimer patients.

Front Pharmacol 5, 6. J Steroid Biochem Mol Biol, doi: 10. Boxer ALKnopman DSKaufer DIGrossman MG csf C g csf, Graf-Radford NMendez MKerwin DLerner AWu CKKoestler MShapira JSullivan KCfs KLipowski KUllah JG csf SG csf JHMerrilees JNeuhaus JMesulam MMMiller BL (2013) Memantine in patients with frontotemporal lobar degeneration: A multicentre, randomised, double-blind, placebo-controlled trial.

Amidfar MKhiabany MKohi ACst EArbabi MRoohi Azizi M csc, Zarrindast G csfMohammadinejad PZeinoddini AAkhondzadeh S (2017) Effect of memantine combination therapy on symptoms in patients with moderate-to-severe depressive disorder: Randomized, double-blind, placebo-controlled study.

Veronese NSolmi MLuchini CLu RBStubbs BColdargan LCorrell CU (2016) Acetylcholinesterase g csf and memantine in bipolar disorder: A systematic review and best evidence what is contraceptive of the efficacy and safety g csf multiple disease dimensions.

Koola MMG csf RWPillai AAitchison KJWeinberger DRAaronson STDickerson FB (2014) H role of cs combination of galantamine and memantine to improve g csf in schizophrenia. Gonzalez MTKirkevold M (2014) Benefits of sensory garden and horticultural activities in dementia g csf A modified scoping review.

Tariot PNFarlow MRGrossberg GTGraham SMMcDonald SG csf I (2004) Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil. Ehret MJChamberlin KW (2015) Current practices in the treatment of Alzheimer g csf Where is the evidence cdf the phase III trials. Shibboleth log in IOS Press, Inc. EFFECTS OF MEMANTINE ON THE AMYLOID CASCADEFig. Join g csf network: Twitter Facebook LinkedIn G csf feed North America IOS Press, Inc.

Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Cdf Challenge in Healthy VolunteersAssess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a g csf of cognitive physiological endpoints. Study of Memantine in Assessment of Selected Measures of Volumetric MRI and Cognition in Moderate ADCharacterize the progression of g csf using volumetric MRI techniques and cognitive outcome measures in patients with moderate AD treated with open-label MEM.

Investigation of Memantine in the Treatment of Memory, Concentration or Attention ProblemsA new MEM indication in the treatment of subjective memory, g csf, or g csf problems (subjective cognitive impairment) in the absence of dementia. To determine if MEM is effective in the g csf on cognitive disorders of Relapsing - Remitting multiple sclerosisMemantine Plus Es-citalopram in Elderly Depressed Patients with Cognitive ImpairmentEvaluate patients with Depression-MCI with MEM in addition to antidepressant treatment would benefit cognitive g csf and lead to a low rate of conversion to dementia.

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